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IN-VITRO RESEARCH ONLY — NOT FOR HUMAN USE
ARA-290
Product information
$72.99
Product description
ARA-290 research compound, also known as Cibinetide. Supplied as a lyophilized peptide reference material for laboratory research applications.
This product is purity-tested for compound identity and is intended for in vitro experimentation, analytical reference, or scientific characterization studies.
For laboratory research use only. Not for human or veterinary use.
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IN-VITRO RESEARCH ONLY — NOT FOR HUMAN USE
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ARA-290
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- Characteristics
- How does ARA-290 work?
- Preparation
- Summary
- Certificate of Analysis (COA)
- Resource
Table of Contents
- Characteristics
- How does ARA-290 work?
- Preparation
- Summary
- Certificate of Analysis (COA)
- Resource
Characteristics
| Molecular Formula | C51H84N16O21 |
| CAS | 1208243-50-8 |
| Molar Mass | 1686.97 g/mol |
| Chemical Formula | C51H84N16O21 |
| Amino Acid Sequence | Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser |
| Synonyms | Pyroglutamate Helix B Surface Peptide, pHBSP, ARA 290, Cibinetide |
| Solubility | Water-soluble |
| Organoleptic Profile | White to off-white powder |
| Composition | Lyophilized powder - requires reconstitution |
How does ARA-290 work?
ARA-290 exerts its effects by selectively activating the innate repair receptor (IRR), a heteromeric complex composed of EPO receptor (EPOR) and β common receptor (βcR) subunits. This specific interaction triggers a cascade of signaling events that lead to anti-inflammatory, tissue-protective, and repair-promoting effects. ARA-290 has been shown to modulate the immune response by reducing the production of pro-inflammatory cytokines and increasing the expression of anti-inflammatory mediators. Additionally, it promotes the survival and function of various cell types, including endothelial cells, cardiomyocytes, and neurons, under stress conditions.
Preparation
ARA-290 Experimental Reagent: Preparation Guidelines Important: Please read these instructions carefully before handling the ARA-290 experimental reagent.
Dissolution:
Due to the high density of ARA-290, dissolve 12mg of the reagent in a minimum of 3ml of bacteriostatic water (BAC water).
Preparation Steps:
Remove the experimental reagent from storage and allow it to reach room temperature (approximately 2-3 hours).
Once at room temperature, add the appropriate amount of BAC water.
After reconstitution, keep the solution at room temperature. Do not refrigerate or refreeze.
Caution:
Reconstituting or storing the reagent in low-temperature environments may cause cloudiness.
Avoid exposing the reconstituted solution to cold temperatures to maintain its clarity and effectiveness.
For optimal results, please follow these guidelines closely.
Summary
ARA 290 peptide is a promising synthetic peptide that mimics the tissue-protective and repair-promoting properties of EPO without stimulating erythropoiesis. By selectively activating the innate repair receptor, ARA-290 exerts potent anti-inflammatory, neuroprotective, cardioprotective, and renoprotective effects in various preclinical models. Clinical studies have also demonstrated its potential in tissue-protective effects and wound research. With its favorable safety profile and wide-ranging therapeutic potential, ARA-290 represents an exciting avenue for the development of novel treatments for a variety of conditions characterized by tissue damage and inflammation.
For laboratories searching for ara 290 for sale or looking to buy ara 290, sourcing from a reputable research-grade supplier with verified purity and analytical validation is essential to ensure experimental accuracy.
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