All products on this site are intended for research and development purposes only and are not meant for human consumption of any kind. The statements made within this website have not been evaluated by the U.S. Food and Drug Administration (FDA). Neither the statements nor the products offered by this company are intended to diagnose, treat, cure, or prevent any disease.
Popular
New
IN-VITRO RESEARCH ONLY — NOT FOR HUMAN USE
PT-141
Product information
$38.49
Limited time offer
$54.99
Save 30%Product description
PT-141 research compound, also known as Bremelanotide. Supplied as a lyophilized peptide reference material for laboratory research applications.
This product is purity-tested for compound identity and is intended for in vitro experimentation, analytical reference, or scientific characterization studies.
For laboratory research use only. Not for human or veterinary use.
Size:
PT-141 (10mg)
$38.49
Ships if ordered within
Free FedEx 2Day® on orders $200+
Free FedEx Standard Overnight® on orders $500+
Third party tested
- Buy 3+ for $34.64 each and save 10%
- Buy 5+ for $32.72 each and save 15%
- Buy 10+ for $30.79 each and save 20%
Bacteriostatic Water
For every $400 you spend, get 1 FREE bottle of bacteriostatic water to reconstitute your peptides.
IN-VITRO RESEARCH ONLY — NOT FOR HUMAN USE
Peptides. Deep Dive
Research-based Podcast
PT-141
Listen
Introduction to Peptides
How peptides work
Rated: 4.8/5
Advanced Laboratory Testing
Testing
Assay
Test
Test
Screening
- Characteristics
- How does PT-141 work?
- Research
- Summary
- Certificate of Analysis (COA)
- Resource
Table of Contents
- Characteristics
- How does PT-141 work?
- Research
- Summary
- Certificate of Analysis (COA)
- Resource
Characteristics
Molecular Formula | C50H68N14O10 |
CAS Number | 189691-06-3 |
Molar Mass | 1025.2 g/mol |
Amino Acid Sequence | Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH |
Synonyms | Bremelanotide, PT-141, PT141, PT 141 |
Solubility | Water-soluble |
Organoleptic Profile | White to off-white powder |
Composition | Lyophilized powder - requires reconstitution |
How does PT-141 work?
PT-141 primarily acts as a melanocortin receptor agonist, with highest affinity for the melanocortin 4 receptor (MC4R) and melanocortin 1 receptor (MC1R). Research suggests the following mechanisms:
1. Central Nervous System: PT-141 activates MC4R in specific brain regions, particularly the hypothalamus and brainstem areas involved in sexual response. This activation is thought to influence neural pathways related to sexual desire and arousal.
2. Neurotransmitter Modulation: Studies indicate that PT-141 may increase dopamine release in the medial preoptic area, a region crucial for sexual motivation.
3. Peripheral Effects: PT-141's interaction with MC1R on melanocytes has been studied for potential effects on skin pigmentation.
Research
1. HSDD in Premenopausal Women:
Multiple Phase III clinical trials have evaluated PT-141's efficacy for HSDD.
Studies typically measured changes in sexual desire and related distress using validated scales like the Female Sexual Function Index (FSFI) and Female Sexual Distress Scale-Desire/Arousal/Orgasm (FSDS-DAO).
Research has examined various dosing regimens and administration methods.
2. Other Areas of Investigation:
Male Sexual Function: Some studies have explored potential effects on erectile function, though this is not an FDA-approved use.
Dermatology: Limited research has investigated PT-141's influence on melanogenesis and potential applications in pigmentation disorders.
Cardiovascular Effects: Studies have examined PT-141's impact on blood pressure and heart rate, primarily for safety monitoring.
Summary
PT-141 (Bremelanotide) is a synthetic peptide that has been the subject of extensive clinical research, particularly in the field of female sexual health. It is approved use for HSDD in premenopausal women represents a significant development in this therapeutic area. Ongoing studies continue to explore its mechanisms of action, potential applications, and long-term safety profile.
Resource
Free Peptide Research Ebook
Become a member and receive your free copy of our exclusive Peptides eBook.
Why become a member?
Full access to research peptide catalog
Tips on scientific peptide experimentation
Free ebook on peptide research
10% off your next purchase
Blogs and podcasts on peptide science
Research Peptides Supported by Verifiable Testing
Power Peptides™ is more than just a U.S. supplier of research peptides. We are helping to power the next wave of peptide research by providing peptides that support our clients’ work.
Consistent Quality Standards
Our internal processes and meticulous material sourcing practices drive consistency. Our peptides meet rigorous internal quality standards.
Independently Verified
Every product undergoes extensive testing, both in-house and through independent, third-party laboratories.
Fast Shipping & Support
We provide fast and reliable shipping, using established couriers and high-quality packaging materials. This helps to ensure that your peptides arrive promptly and in optimal condition.