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P21 Peptide Spray 10ml (25mg)

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$163.99

Product description

The P21 peptide spray is a high-purity research compound derived from Cerebrolysin's active fragment, specifically formulated for neuroscience and cognitive function studies. This research-grade solution (>98% purity) is designed for enhanced brain-blood barrier penetration and optimal bioavailability in laboratory applications, making it ideal for investigating neurogenesis, neural plasticity, neuroprotection, and BDNF modulation pathways. Suitable for in vitro and preclinical studies, this sterile-filtered solution is specifically intended for academic institutions, research laboratories, and neuroscience facilities conducting authorized studies on neurogenic compounds and cognitive enhancement mechanisms.

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P21 Peptide Spray 10ml (25mg) (25mg/10ml)

$163.99

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This product is not approved for human or animal consumption.Misuse, misbranding, or mislabeling as a drug, food, or cosmetic is strictly prohibited. All information provided is for educational purposes only.

This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals.

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Table of Contents

  1. Characteristics
  2. How does P21 work?
  3. Benefits
  4. Side Effects
  5. Summary
  6. References
  7. Certificate of Analysis (COA)
  8. Resource

Characteristics

Molecular Formula

C30H54N6O5

CAS Number

1174043-81-0

Molar Mass

578.79 g/mol

Amino Acid Sequence

Ala-Glu-Thr-Gln-Leu-Gln-His-Ser-Leu-Gly-Ala-Leu-Pro-Arg-Arg-Arg

Synonyms

P021, P21

Solubility

Water-soluble

Organoleptic Profile

White powder

Composition

Synthetic peptide

How does P21 work?

P21 exerts its effects through various mechanisms of action. One of the primary ways P21 functions is by promoting the survival and growth of neurons. Studies have shown that P21 can protect neurons from oxidative stress and apoptosis, which are common factors contributing to neuronal damage and degeneration. Additionally, P21 has been found to enhance the effects of CNTF, a protein that plays a crucial role in the development and maintenance of the nervous system. By modulating CNTF signaling, P21 may help to support neuronal survival and function.

Furthermore, P21 has been investigated for its potential to stimulate the proliferation and differentiation of neural stem cells. By promoting the growth and development of new neurons, P21 may contribute to the regeneration and repair of damaged neural tissues. This property of P21 has garnered significant attention in the field of regenerative medicine, particularly in the context of neurodegenerative disorders.

Benefits

The potential benefits of P21 are numerous and have been explored in various research studies. One of the most promising applications of P21 is in the treatment of neurodegenerative disorders, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). By promoting neuronal survival and protecting against oxidative stress and apoptosis, P21 may help to slow down or prevent the progression of these debilitating conditions.

In addition to its neuroprotective properties, P21 has also been investigated for its potential to enhance cognitive function. Studies have suggested that P21 may improve memory and learning abilities by stimulating the growth and development of new neurons in the brain. This finding has significant implications for the treatment of cognitive decline associated with aging and neurodegenerative disorders.

Moreover, P21 has shown promise in the field of regenerative medicine. By promoting the proliferation and differentiation of neural stem cells, P21 may contribute to the regeneration of damaged neural tissues. This property of P21 could potentially be harnessed to develop novel therapies for spinal cord injuries, stroke, and other conditions characterized by neuronal damage.

Side Effects

While P21 has demonstrated numerous potential benefits, it is important to note that the peptide is currently intended for research purposes only. The safety and efficacy of P21 in mammals have not been fully established, and further studies are needed to assess any potential side effects or adverse reactions. As with any research compound, caution should be exercised, and appropriate safety protocols should be followed when handling and administering P21.

Summary

P21 (P021) is a promising synthetic peptide with the molecular formula C30H54N6O5. Research studies have highlighted the potential of P21 in various therapeutic applications, particularly in the field of neuroscience. P21 has been shown to exhibit neuroprotective properties, promote neuronal survival, and enhance the effects of CNTF. Additionally, P21 has been investigated for its ability to stimulate the growth and development of new neurons, making it a candidate for regenerative medicine approaches. While the benefits of P21 are numerous, further research is needed to fully understand its mechanisms of action and assess its safety and efficacy in mammals. As a research compound, P21 holds significant promise for advancing our understanding of neurodegenerative disorders and developing novel therapeutic strategies.

References

  1. Kazim SF, Iqbal K. Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's disease. Mol Neurodegener. 2016 Jul 11;11(1):50. doi: 10.1186/s13024-016-0119-y. PMID: 27400746; PMCID: PMC4940708.

  2. Baazaoui N, Iqbal K. Alzheimer's Disease: Challenges and a Therapeutic Opportunity to Treat It with a Neurotrophic Compound. Biomolecules. 2022 Oct 2;12(10):1409. doi: 10.3390/biom12101409. PMID: 36291618; PMCID: PMC9599095.

  3. Bolognin S, Buffelli M, Puoliväli J, Iqbal K. Rescue of cognitive-aging by administration of a neurogenic and/or neurotrophic compound. Neurobiol Aging. 2014 Sep;35(9):2134-46. doi: 10.1016/j.neurobiolaging.2014.02.017. Epub 2014 Mar 2. PMID: 24702821.

  4. Wei W, Liu Y, Dai CL, Baazaoui N, Tung YC, Liu F, Iqbal K. Neurotrophic Treatment Initiated During Early Postnatal Development Prevents the Alzheimer-Like Behavior and Synaptic Dysfunction. J Alzheimers Dis. 2021;82(2):631-646. doi: 10.3233/JAD-201599. PMID: 34057082; PMCID: PMC8385525.

  5. Liu Y, Wei W, Baazaoui N, Liu F, Iqbal K. Inhibition of AMD-Like Pathology With a Neurotrophic Compound in Aged Rats and 3xTg-AD Mice. Front Aging Neurosci. 2019 Nov 19;11:309. doi: 10.3389/fnagi.2019.00309. PMID: 31803044; PMCID: PMC6877482.

  6. Kazim SF, Blanchard J, Dai CL, Tung YC, LaFerla FM, Iqbal IG, Iqbal K. Disease modifying effect of chronic oral treatment with a neurotrophic peptidergic compound in a triple transgenic mouse model of Alzheimer's disease. Neurobiol Dis. 2014 Nov;71:110-30. doi: 10.1016/j.nbd.2014.07.001. Epub 2014 Jul 15. PMID: 25046994.

  7. Silvia Bolognin, Mario Buffelli, Jukka Puoliväli, Khalid Iqbal, Rescue of cognitive-aging by administration of a neurogenic and/or neurotrophic compound, Neurobiology of Aging, Volume 35, Issue 9, 2014, Pages 2134-2146, ISSN 0197-4580, https://doi.org/10.1016/j.neurobiolaging.2014.02.017.

Resource

All products on this site are for research and development use only. Products are not for human consumption of any kind. The statements made on this website have not been evaluated by the US Food and Drug Administration....
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