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IN-VITRO RESEARCH ONLY — NOT FOR HUMAN USE
Selank
Product information
$98.99
Product description
Selank is a synthetic peptide and an analog of the endogenous tetrapeptide tuftsin, with the sequence Thr-Lys-Pro-Arg. This neuropeptide has been studied for its role in neurological and behavioral pathways. Selank exhibits pronounced anxiolytic and nootropic effects, as well as immunomodulatory and anti-inflammatory properties, making it a promising candidate for various neuropsychiatric and cognitive disorders. Requires reconstitution before use.
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- Characteristics
- How is Selank Used in Research?
- Areas of Study
- Summary
- References
- Certificate of Analysis (COA)
- Resource
Table of Contents
- Characteristics
- How is Selank Used in Research?
- Areas of Study
- Summary
- References
- Certificate of Analysis (COA)
- Resource
Characteristics
Molecular Formula | C₂₃H₄₁N₉O₇ |
CAS Number | 129954-34-3 |
Molar Mass | 555.64 g/mol |
Amino Acid Sequence | Thr-Lys-Pro-Arg |
Synonyms | TP-7, Immunomodulator Selank, Antidepressant Selank, Selanc |
Solubility | Water-soluble |
Organoleptic Profile | White to off-white powder |
Composition | Lyophilized powder - requires reconstitution |
How is Selank Used in Research?
Selank exerts its effects through multiple mechanisms of action. It has been shown to modulate the expression of brain-derived neurotrophic factor (BDNF) and its receptor TrkB, which are crucial for neuronal survival, growth, and synaptic plasticity. Selank also interacts with the GABAergic system, enhancing the inhibitory neurotransmission and thus producing anxiolytic effects. Additionally, Selank has been found to regulate the activity of serotonin and dopamine, neurotransmitters involved in mood regulation and cognitive function.Furthermore, Selank exhibits immunomodulatory and anti-inflammatory properties. It has been shown to modulate the production of cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α), and to enhance the activity of natural killer cells, thereby boosting the immune response. Selank also demonstrates antioxidant effects, protecting cells from oxidative stress-induced damage. These mechanisms reflect what Selank peptide does in research. Appropriate Selank dosage depends on the experimental model.
Areas of Study
- Stress pathway activity: Scientists have investigated Selank in experimental settings for its effects on stress-related signaling and behavioral regulation, including pathways associated with inhibitory neurotransmission.
- Mood modulation: Selank has been examined for its involvement in neural pathways linked to mood regulation, particularly those related to monoaminergic function and BDNF expression.
- Cognitive processing: Selank’s activity in cognitive pathways has been extensively explored. Experimental models have examined its involvement in mechanisms underlying information processing, including spatial and verbal task performance, as well as attention-related functions.
- Neuronal Function: Activity in pathways associated with neuronal integrity has been explored, including interactions with BDNF expression and oxidative stress responses. Experimental models have examined its role in supporting cellular resilience and maintaining normal neuronal function under stress-related conditions.
- Immune signaling: Selank has been studied for its interaction with immune-related signaling pathways, including those involved in cytokine activity and cellular response processes. Its role in broader immune system function and inflammatory signaling continues to be explored in experimental settings.
Summary
Selank is a synthetic peptide that has been widely studied for its involvement in neurobiological and immune-related pathways. Its activity has been explored in relation to stress response, mood-associated processes, cognitive function, and neuronal signaling, as well as interactions with immune system pathways. While existing findings provide insight into its biological activity, further investigation is required to better characterize its mechanisms and effects across different experimental models. As a research compound, Selank continues to be of interest in the study of complex neurological and biochemical systems.
References
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